^Ingredients that are not grown on our farm, or if our supply is short, are sourced from certified organic farms.
Standard Process conducted an open-label pilot study to evaluate the efficacy of Spanish black radishes in inducing Phase I and II enzymes in healthy male subjects (n=20). Acetaminophen is metabolized in the liver through pathways that involve Phase II enzymes, including conjugation, sulfation, and glucuronidation, that produce measurable metabolites in blood and urine. Consumption of Spanish black radishes increased liver detoxification capacity and positively altered the metabolism of acetaminophen via increased urinary excretion.4
Spanish black radishes (Raphanus sativus l. var. niger) are particularly rich in a class of phytonutrients called glucosinolates, which have been associated with several beneficial health outcomes attributed to consumption of cruciferous vegetables.1, 2
The main mechanism of action through which metabolites of glucosinolates mediate their beneficial effects may be via the induction of metabolic detoxification Phase I and II enzymes, as well as induction of antioxidant enzymes.1-5
The glucosinolates in Spanish black radishes are unique in both content and concentration in comparison to other cruciferous vegetables.2 For example, the glucosinolates in Spanish black radishes make up over 4% in sprout of their total dry weight; glucosinolates in more common crucifers, such as broccoli, only constitute 1% of the broccoli sprout.2-4 In contrast to more common crucifers, >65% of the glucosinolates present in Spanish black radishes is glucoraphasatin.2 The metabolite of glucoraphasatin, 4-methylthio-3-butenyl isothiocyanate (raphasatin), carries similar potency as sulforaphane (the metabolite of glucoraphanin that is particularly abundant in broccoli) on Phase II gene expression.2,4
Phase I and phase II detoxification enzymes work together to help the body break down and manage compounds that need to be removed. Mice fed a diet containing 20% Spanish black radishes for two weeks showed significant enhancement of the metabolism of toxins as demonstrated by significantly increased expression of Phase I and II detoxification enzymes.5
One to three servings per day, or as directed.
Acute Use: Three tablets per day to support toxin elimination*
Long-Term Use: one tablet per day to support liver health*
Keep out of reach of children.
Each Serving Size (1 Tablet) contains: Calories 5, Total Carbohydrate <1 g, Vitamin C 5 mg, Organic Spanish black radish (root) 750 mg. Other Ingredients: Organic honey, organic camu camu (berry) organic manioc (root), organic rice extract, organic rice hulls, organic acacia fiber, and organic sunflower oil.
Please consult the actual product label for the most accurate product information.
*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.